FDA Aapproves Motegrity

The U.S. Food and Drug Administration (FDA) has approved Motegrity (prucalopride), a selective serotonin-4 (5-HT4) receptor agonist for the treatment of adults with Chronic Idiopathic Constipation (CIC).

Motegrity is a prescription medicine used in adults to treat a type of constipation called chronic idiopathic constipation (CIC). Idiopathic means the cause of the constipation is unknown.

It is not known if this medicine is safe and effective in children.

Do not take Motegrity if you:

are allergic to prucalopride or any of the other ingredients. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat.

have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohn’s disease or ulcerative colitis.

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

have or have had depression, suicidal thoughts or actions, or mood problems.

have kidney problems. Your healthcare provider may give you a lower dose.

are pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby.

are breastfeeding or plan to breastfeed. Prucalopride can pass into your breastmilk. Talk with your healthcare provider about the best way to feed your baby if you take Motegrity.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Take one Motegrity tablet each day or as directed by your healthcare provider.

Take this medicine exactly as your healthcare provider tells you to take it.

Take the tablets with or without food.

Motegrity side effects

Motegrity may cause serious side effects, including:

unusual changes in mood or behavior, thoughts of hurting yourself, trying to hurt yourself, or suicide. Stop taking Motegrity right away and tell your healthcare provider immediately if your depression gets worse, you feel sad, hopeless or begin to have thoughts of suicide, thoughts of hurting yourself or have tried to hurt yourself.

The most common side effects include:

headache

stomach area (abdominal) pain or bloating

nausea

diarrhea

dizziness

vomiting

gas

fatigue

These are not all the possible side effects. Call your doctor for medical advice about side effects.

 

FDA Aapproves Motegrity

The U.S. Food and Drug Administration (FDA) has approved Motegrity (prucalopride), a selective serotonin-4 (5-HT4) receptor agonist for the treatment of adults with Chronic Idiopathic Constipation (CIC). Motegrity is a prescription medicine used in adults to treat a type of constipation called chronic idiopathic constipation (CIC). Idiopathic means the cause of the constipation is unknown. It is not known if this medicine is safe and effective in children. Do not take Motegrity if you: are allergic to prucalopride or any of the other ingredients. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat. have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohns disease or ulcerative colitis. Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you: have or have had depression, suicidal thoughts or actions, or mood problems. have kidney problems. Your healthcare provider may give you a lower dose. are pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby. are breastfeeding or plan to breastfeed. Prucalopride can pass into your breastmilk. Talk with your healthcare provider about the best way to feed your baby if you take Motegrity. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Take one Motegrity tablet each day or as directed by your healthcare provider. Take this medicine exactly as your healthcare provider tells you to take it. Take the tablets with or without food. Motegrity side effects Motegrity may cause serious side effects, including: unusual changes in mood or behavior, thoughts of hurting yourself, trying to hurt yourself, or suicide. Stop taking Motegrity right away and tell your healthcare provider immediately if your depression gets worse, you feel sad, hopeless or begin to have thoughts of suicide, thoughts of hurting yourself or have tried to hurt yourself. The most common side effects include: headache stomach area (abdominal) pain or bloating nausea diarrhea dizziness vomiting gas fatigue These are not all the possible side effects. Call your doctor for medical advice about side effects.